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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX59 All Species: 16.06
Human Site: S156 Identified Species: 23.56
UniProt: Q5T1V6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T1V6 NP_001026895.2 619 68810 S156 S N P Q K A D S E P E S P L N
Chimpanzee Pan troglodytes XP_001143546 619 68778 S156 S N P Q K A D S E P E S P L N
Rhesus Macaque Macaca mulatta XP_001109688 319 35696
Dog Lupus familis XP_537128 620 68704 S157 S A P H K A N S E P E S P L N
Cat Felis silvestris
Mouse Mus musculus Q9DBN9 619 68216 A156 S S P Q R V A A E P E S P L D
Rat Rattus norvegicus Q66HG7 589 65047 S156 S S P Q G A A S E P E S P L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520980 538 59378 Q146 C K A K H L L Q V R D K E E G
Chicken Gallus gallus XP_422189 625 69278 S161 A H L A K G E S Q E E S H L L
Frog Xenopus laevis NP_001106297 254 27959
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 R283 T G F Q T K Q R K V L E P V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09052 661 72313 N209 Y I P P E P S N D A I E I F S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198909 620 68882 E175 A E N P E S D E E P R P I V S
Poplar Tree Populus trichocarpa XP_002320399 524 57616 L131 L S F S S C N L P E K L L H N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EBD3 505 55199 T113 P P P V L T F T S C G L P P K
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 P150 D A S G K D V P E P I L D F S
Red Bread Mold Neurospora crassa Q7SEL0 728 82594 M249 Q H R R I K E M E Q R K N L G
Conservation
Percent
Protein Identity: 100 99 51 89.8 N.A. 83.6 79.8 N.A. 61.8 72.3 30.2 22.3 N.A. 27.6 N.A. N.A. 32.1
Protein Similarity: 100 99.8 51.3 93.3 N.A. 89.6 86.7 N.A. 71.5 84.3 35.3 37.3 N.A. 45.8 N.A. N.A. 52.4
P-Site Identity: 100 100 0 80 N.A. 60 73.3 N.A. 0 33.3 0 13.3 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 0 86.6 N.A. 86.6 86.6 N.A. 13.3 60 0 40 N.A. 33.3 N.A. N.A. 53.3
Percent
Protein Identity: 40.7 N.A. N.A. 38.1 26.3 26.9
Protein Similarity: 58 N.A. N.A. 56.2 46.3 46.4
P-Site Identity: 6.6 N.A. N.A. 13.3 20 13.3
P-Site Similarity: 26.6 N.A. N.A. 20 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 7 7 0 25 13 7 0 7 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 19 0 7 0 7 0 7 0 19 % D
% Glu: 0 7 0 0 13 0 13 7 50 13 38 13 7 7 0 % E
% Phe: 0 0 13 0 0 0 7 0 0 0 0 0 0 13 0 % F
% Gly: 0 7 0 7 7 7 0 0 0 0 7 0 0 0 13 % G
% His: 0 13 0 7 7 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 0 7 0 0 7 0 0 0 0 0 13 0 13 0 0 % I
% Lys: 0 7 0 7 32 13 0 0 7 0 7 13 0 0 7 % K
% Leu: 7 0 7 0 7 7 7 7 0 0 7 19 7 44 7 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 13 7 0 0 0 13 7 0 0 0 0 7 0 25 % N
% Pro: 7 7 44 13 0 7 0 7 7 44 0 7 44 7 0 % P
% Gln: 7 0 0 32 0 0 7 7 7 7 0 0 0 0 0 % Q
% Arg: 0 0 7 7 7 0 0 7 0 7 13 0 0 0 0 % R
% Ser: 32 19 7 7 7 7 7 32 7 0 0 38 0 0 19 % S
% Thr: 7 0 0 0 7 7 0 7 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 7 7 0 7 7 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _